Product Description

Cathepsin B Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90200-50, BS90200-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P07858(Human)

Host: Rabbit

Reactivity: Human

Applications: WB, ICC/IF, IHC

All Applications: WB:1:500-1:1,000
ICC:1:50-1:200
IHC:1:50-1:200

Background: The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsin B is expressed in luminal epithelial cells, indicating that cathepsin B is a marker for secretory cell death.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: Cathepsin B polyclonal antibody detects endogenous levels of Cathepsin B protein.

Bioworld Molecular Weight: 38 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Cathepsin B on different cells lysates using anti-Cathepsin B antibody at 1/500 dilution.
Positive control:
Lane 1: HepG2
Lane 2: Hela
Lane 3:A549, Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-Cathepsin B antibody. Counter stained with hematoxylin.

Alternative Name: APPS, CTSB, Amyloid precursor protein secretase, APP secretase, APPS, CATB, Cathepsin B heavy chain, Cathepsin B1, CathepsinB, CPSB, CTSB, cysteine protease, OTTHUMP00000116009, OTTHUMP00000229510, OTTHUMP00000229511, OTTHUMP00000229512, OTTHUMP00000229514, OTTHUMP00000229515, OTTHUMP00000229516, Preprocathepsin B,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified