Cathepsin D Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA22784-50, RA22784-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: cathepsin D (CTSD) Homo sapiens This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015], Reactivity: Human, Mouse Host: Rabbit Applications: WB, IHC-p, IF (paraffin section), ELISA Alternate Names: CTSD, CPSD, Cathepsin D Clonality: Polyclonal Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. Molecular Weight: 44 Protein Molecular Weight (kDa): 44 Storage: -20°C/1 year Human Gene ID: 1509 Human SwissProt Number: P07339 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only