Cathepsin E Polyclonal Antibody - E-AB-13974

Cathepsin E Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-13974-60, E-AB-13974-120, E-AB-13974-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CTSE

Target Synonym: CATE; CATE; Cathepsin E; Cathepsin E form II; CTSE; Erythrocyte membrane aspartic proteinase; Slow moving proteinase

Research Areas: Cancer, Immunology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P14091

Background: The protein encoded by this gene is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen. Transcript variants utilizing alternative polyadenylation signals and two transcript variants encoding different isoforms exist for this gene.

Concentration: 0.6 mg/mL

Immunogen: Recombinant protein of human CTSE

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:100-1:300

Calculated MW: 43kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only