Cathepsin H (Y205) Polyclonal Antibody-BS3530

Cathepsin H (Y205) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS3530-50, BS3530-100

Sizes: 50µl, 100µl

Swiss-Prot: P09668

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC

Background: The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in various cellular events such as peptide biosynthesis and protein degradation. The propeptide region of cathepsin H is highly homologous to other cathepsins. This region is thought to play a role in the processing of cysteine proteases. Cathepsin H is thought to be involved in several pathological conditions, including neuro degenerative disorders and cancer.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Cathepsin H (Y205) polyclonal antibody detects endogenous levels of Cathepsin H protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of Cathepsin H (Y205) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.

Bioworld Molecular Weight: ~ 25, 37 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Pro-cathepsin H; Cathepsin H; Cathepsin H heavy chain; CTSH; CPSB; CATH

Immunogen: Synthetic peptide, corresponding to amino acids 171-210 of Human Cathepsin H.

Conjugate: Unconjugated

Modification: Unmodified