Cathepsin L Polyclonal Antibody - E-AB-10211

Cathepsin L Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-10211-60, E-AB-10211-120, E-AB-10211-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CTSL

Target Synonym: cathepsin L; 1 b; Cathepsin L1; Cathepsin L1 light chain; CathepsinL; CATL; CATL1; cb15; CTSL; CTSL1; ctsl1b; FLJ31037; hgg1; Major excreted protein; MEP; MGC123162; wu:fb30g09

Research Areas: Cancer, Neuroscience, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P07711

Background: The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene.

Concentration: 0.5 mg/mL

Immunogen: Recombinant protein of human CTSL

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only