Cav1.3 rabbit pAb - ES20797

Cav1.3 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20797-50, ES20797-100

Citations, Manuals and MSDS Available upon request.

Background: calcium voltage-gated channel subunit alpha1 D (CACNA1D) Homo sapiens Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012],

Alternate Name: Voltage-dependent L-type calcium channel subunit alpha-1D (Calcium channel, L type, alpha-1 polypeptide, isoform 2; Voltage-gated calcium channel subunit alpha Cav1.3)

Source: Rabbit

Applications: IHC; IF

Dilution: IHC 1:100-200

Reactivity: Human; Rat; Mouse

Immunogen: Synthetic Peptide of Cav1.3 AA range: 1060-1140

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 245kD

Human Gene ID: 776

Human SWISS Prot NO: Q01668

Subcellular Location: Membrane; Multi-pass membrane protein.

Research Use Only