CAV1 Polyclonal Antibody - E-AB-30778

CAV1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-30778-60, E-AB-30778-120, E-AB-30778-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: Caveolin-1

Target Synonym: BSCL3; CAV; CAV1; CAV1; caveolae protein; 22 kD; caveolin 1 alpha isoform; caveolin 1 beta isoform; Caveolin 1 caveolae protein 22kDa; Caveolin-1; Caveolin1; cell growth-inhibiting protein 32; CGL3; LCCNS; MSTP085; OTTHUMP00000025031; PPH3; VIP 21; VIP21

Research Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction, Tags and Cell Markers

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC-p, IF, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q03135

Background: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.

Concentration: 1 mg/mL

Immunogen: Synthesized peptide derived from the C-terminal region of human Caveolin-1

Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-2000, IHC 1:50-300, IF 1:50-300

Calculated MW: 20kDa

Observed MW: 25kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only