Cav3.2 rabbit pAb - ES20795

Cav3.2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES20795-50, ES20795-100

Citations, Manuals and MSDS Available upon request.

Background: calcium voltage-gated channel subunit alpha1 H (CACNA1H) Homo sapiens This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE). [provided by RefSeq, Jul 2008],

Alternate Name: CACNA1H; Voltage-dependent T-type calcium channel subunit alpha-1H; Low-voltage-activated calcium channel alpha1 3.2 subunit; Voltage-gated calcium channel subunit alpha Cav3.2

Source: Rabbit

Applications: IHC; IF

Dilution: IHC 1:50-100

Reactivity: Human; Rat; Mouse

Immunogen: Synthetic Peptide of Cav3.2 AA range: 1718-1768

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 260kD

Human Gene ID: 8912

Human SWISS Prot NO: O95180

Subcellular Location: Cell membrane; Multi-pass membrane protein. Interaction with STAC increases expression at the cell membrane.

Research Use Only