CaVAlpha2delta1 Polyclonal Antibody - BT-AP07172

CaVAlpha2delta1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP07172-20, BT-AP07172-50, BT-AP07172-100

Citations, Manuals and MSDS Available upon request.

Background: The preproprotein encoded by this gene is cleaved into multiple chains that comprise the alpha-2 and delta subunits of the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. Mutations in this gene can cause cardiac deficiencies, including Brugada syndrome and short QT syndrome. Alternate splicing results in multiple transcript variants, some of which may lack the delta subunit portion.

Research Areas: Neuroscience; Signal transduction

Target Protein: CACNA2D1

Applications: WB, IHC-p, IF

Reactivity: Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Voltage-dependent calcium channel subunit alpha-2/delta-1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P54289; Mouse: O08532; Rat: P54290

Synonyms: Voltage-dependent calcium channel subunit alpha-2/delta-1;Voltage-gated calcium channel subunit alpha-2/delta-1 [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-1; Voltage-dependent; Voltage-dependent calcium channel subunit alpha-2/delta-1; Voltage-gated calcium channel subunit alpha-2/delta-1; Voltage-dependent calcium channel subunit alpha-2-1; Voltage-dependent calcium channel subunit delta-1;

GeneID: Human: 781

Research Use Only