Product Description

Caveolin 1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16545-50, BZ16545-100

Product: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Swiss-Prot: Q03135

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-P, ICC/IF

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Background: Caveolin-1 may act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 20 kDa; Observed MW: 25 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Caveolin1 in A431 lysates using Caveolin 1 antibody., Immunohistochemistry analysis of paraffin-embedded mouse lung using Caveolin1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Immunofluorescence analysis of Caveolin 1 in A431 using Caveolin1 antibody.

Alternative Name: CAV1; CAV; Caveolin-1

Immunogen: A synthesized peptide derived from human Caveolin-1

Conjugate: Unconjugated

Modification: Unmodified