Product Description

CBG Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP01261-20, BT-AP01261-50, BT-AP01261-100

Citations, Manuals and MSDS Available upon request.

Background: The protein (glucosylceramidase beta 3 (gene/pseudogene)) encoded by GBA3 is an enzyme that can hydrolyze several types of glycosides. GBA3 is a polymorphic pseudogene, with the most common allele being the functional allele that encodes the full-length protein. Some individuals, as represented by the reference genome allele, contain a single nucleotide polymorphism that results in a premature stop codon in the coding region, and therefore this allele is pseudogenic due to the failure to produce a functional full-length protein. Alternative splicing of GBA3 results in multiple transcript variants.

Research Areas: Signal Transduction; Metabolism

Target Protein: GBA3

Applications: WB, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: CBG Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 53696

UniProt Accession: Human: Q9H227

Synonyms: GBA3; CBG; CBGL1; Cytosolic beta-glucosidase; Cytosolic beta-glucosidase-like protein 1

GeneID: Human: 57733

Research Use Only