Product Description

CBX6 (K18) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS1904-50, BS1904-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O95503

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC

All Applications: IHC: 1:50~1:200

Background: Polycomb group (PcG) proteins form multiprotein complexes that regulate expression patterns of developmental and cell proliferation genes. CBX6 (chromobox protein homolog 6) is a 412 amino acid protein that is a component of the chromatin-associated PcG complex. Through interaction with PcG, CBX6 modifies chromatin and maintains the transcriptionally repressive state of genes. Members of the chromobox domain protein family are characterized by the presence of a 37 amino acid chromobox (CHRromatin Organization MOdifier) domain. This domain plays a mechanistic role in targeting chromodomain proteins to specific regions of the nucleus.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of CBX6 (K18) pAb in paraffin-embedded human tonsil carcinoma tissue at 1:50.

Bioworld Molecular Weight: ~ 44 kDa

Specificity: CBX6 (K18) polyclonal antibody detects endogenous levels of CBX6 protein.

Alternative Name: Chromobox protein homolog 6; CBX6

Immunogen: Synthetic peptide, corresponding to amino acids 1-50 of Human CBX6.

Conjugate: Unconjugated

Modification: Unmodified