Product Description

CCBE1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60287-50, BS60287-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The gene encoding CCBE1 (Collagen and calcium-binding EGF domain-containing protein 1) is located on chromosome 18 in a region that is frequently found to be deleted in breast and prostate cancers. CCBE1 is a 406 amino acid secreted protein that contains two collagen-like domains and one calcium-binding epidermal growth factor (EGF-like) domain. In general, EGF-like domains include six cysteine residues that are usually involved in disμlfide bonds. Calcium-binding EGF-like domains are subject to amino acid substitutions that disrupt their structure or calcium affinity, therefore altering protein function. Downregμlation of the gene encoding CCBE1 is observed with high frequency in breast cancer, suggesting that loss of CCBE1 resμlts in changes in cell adhesion and mobility due to its characterization as an extracellμlar protein. There are three named isoforms of CCBE1 which are produced as a resμlt of alternative splicing events.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Collagen and calcium-binding EGF domain-containing protein 1, Fμll of fluid protein homolog, KIAA1983, UNQ1921/PRO4395

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human CCBE1.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CCBE1 polyclonal antibody detects endogenous levels of CCBE1 protein.

Molecular Weight: ~ 44 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q6UXH8

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only