CCDC88A Polyclonal Antibody - E-AB-13059

CCDC88A Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-13059-60, E-AB-13059-120, E-AB-13059-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CCDC88A

Target Synonym: AKT iphosphorylation enhancer; Akt phosphorylation enhancer; APE; Ccdc88a; Coiled coil domain containing 88A; Coiled coil domain containing protein 88A; Coiled-coil domain-containing protein 88A; FLJ10392; G alpha interacting vesicle associated protein; G alpha-interacting vesicle-associated protein; Galpha interacting vesicle associated protein; Girders of actin filament; Girdin; GIV; GRDN; GRDN; HkRP1; Hook related protein 1; Hook-related protein 1; KIAA1212

Research Areas: Cancer, Neuroscience, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q3V6T2

Background: This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Concentration: 1 mg/mL

Immunogen: Synthetic peptide of human CCDC88A

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: IHC 1:50-1:200

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only