Product Description

CCK-BR (L54) Polyclonal Antibody

Catalogue Numbers: BS3159-50, BS3159-100

Sizes: 50µl, 100µl

Alternative Name: Gastrin/cholecystokinin type B receptor; CCK-B receptor; CCK-BR; Cholecystokinin-2 receptor; CCK2-R; CCKBR; CCKRB

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P32239

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: CCKBR is a G protein coupled receptor for gastrin and cholecystokinin (CCK), regulatory peptides of the brain and gastrointestinal tract. This protein is a type B gastrin receptor, which has a high affinity for both sulfated and nonsulfated CCK analogs and is found principally in the central nervous system and the gastrointestinal tract. A misspliced transcript variant including an intron has been observed in cells from colorectal and pancreatic tumors. CCKBR is most abundant in brain and stomach but it can also be found in colon, pancreas, thyroid, and various cancers.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CCK-BR (L54) polyclonal antibody detects endogenous levels of CCK-BR protein.

Bioworld Molecular Weight: ~ 48 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of CCK-BR (L54) pAb at 1:500 dilution
Lane 1: Panc1 whole cell lysate(40ug)
Lane 2: SGC7901 whole cell lysate(40ug)
Lane 3: The Brain tissue lysate of Mouse(20ug)
Lane 4: The Brain tissue lysate of Rat(40ug)

Immunogen: Synthetic peptide, corresponding to amino acids 30-80 of Human CCK-BR.

Conjugate: Unconjugated

Modification: Unmodified