Product Description

CCL26 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60482-50, BS60482-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Chemokines have been implicated in the regμlation of stem/progenitor cell proliferation and movement. C-C chemokines myeloid progenitor inhibitory factor-1 (MPIF)-1 and eotaxin-2 (also known as MPIF-2, CK b-6 or small inducible cytokine A24) both map to chromosome 7q11.23. MPIF-1 has chemotactic activity on dendritic cells derived from either peripheral blood monocytes or cord blood CD34+ progenitors. It is also a potent suppressor of bone marrow low proliferative potential colony-forming cells. Eotaxin-2, which promotes chemotaxis and Ca2+ mobilization in human eosinophils, exerts its activity solely through the CCR3 receptor. In addition, eotaxin-2 lacks suppressive activity against immature subsets of myeloid progenitors, which have been stimμlated to proliferate by mμltiple growth factors. A related C-C chemokine, eotaxin-3, shares only 33% amino acid identity with eotaxin-2, but shares many characteristics with eotaxin-2. Eotaxin-3 induces migration of eosinophils and basophils at a 10-fold higher concentration than eotaxin-2. The gene which encodes eotaxin-3 maps to human chromosome 7q11.23.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: C-C motif chemokine 26, CC chemokine IMAC, Eotaxin-3, Macrophage inflammatory protein 4-alpha, MIP-4-alpha, Small-inducible cytokine A26, Thymic stroma chemokine-1, TSC-1, CCL26, SCYA26, UNQ216, PRO242

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in HumanCCL26.

Dilution: WB: 1:500~1:1000
IHC: 1:50~1:203

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 98% (by SDS-PAGE).

Specificity: CCL26 polyclonal antibody detects endogenous levels of CCL26 protein.

Molecular Weight: ~ 11 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -23°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9Y258

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only