CCL26 Polyclonal Antibody
Catalogue Numbers: BS60845-50, BS60845-100
Sizes: 50µl, 100µl
Alternative Name: C-C motif chemokine 26; CC chemokine IMAC; Eotaxin-3; Macrophage inflammatory protein 4-alpha; MIP-4-alpha; Small-inducible cytokine A26; Thymic stroma chemokine-1; TSC-1; CCL26; SCYA26; UNQ216; PRO242
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: Q9Y258
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: Chemokines have been implicated in the regulation of stem/progenitor cell proliferation and movement. C-C chemokines myeloid progenitor inhibitory factor-1 (MPIF)-1 and eotaxin-2 (also known as MPIF-2, CK b-6 or small inducible cytokine A24) both map to chromosome 7q11.23. MPIF-1 has chemotactic activity on dendritic cells derived from either peripheral blood monocytes or cord blood CD34+ progenitors. It is also a potent suppressor of bone marrow low proliferative potential colony-forming cells. Eotaxin-2, which promotes chemotaxis and Ca2+ mobilization in human eosinophils, exerts its activity solely through the CCR3 receptor. In addition, eotaxin-2 lacks suppressive activity against immature subsets of myeloid progenitors, which have been stimulated to proliferate by multiple growth factors. A related C-C chemokine, eotaxin-3, shares only 33% amino acid identity with eotaxin-2, but shares many characteristics with eotaxin-2. Eotaxin-3 induces migration of eosinophils and basophils at a 10-fold higher concentration than eotaxin-2. The gene which encodes eotaxin-3 maps to human chromosome 7q11.23.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CCL26 polyclonal antibody detects endogenous levels of CCL26 protein.
Bioworld Molecular Weight: ~ 11 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of CCL26 polyclonal antibody at 1:500 dilution Lane 1: HEK293T whole cell lysate
Lane 2: RAW264.7 whole cell lysate Lane 3: H9C2 whole cell lysate
Immunogen: A synthetic peptide corresponding to residues in Human CCL26.
Conjugate: Unconjugated
Modification: Unmodified