CCL8/MCP-2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A24871-20, A24871-100
Citations, Manuals and MSDS Available upon request.
Background: This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.
Category: Polyclonal Antibodies
Applications: WB
Cross-reactivity: Human
Protein Weight: 11kDa
Observed Molecular Weight: 11kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 6355
SWISS: P80075
Alternate Names: CCL8; HC14; MCP-2; MCP2; SCYA10; SCYA8; C-C motif chemokine 8; CCL8/MCP-2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000
Research Areas: Immunology & Inflammation, Cytokines, Cell Intrinsic Innate Immunity Signaling Pathway, Chemokines, Chemokine.
NCBI Alias: CCL8
Research Use Only