CCP2 Polyclonal Antibody - BT-AP01318

CCP2 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP01318-20, BT-AP01318-50, BT-AP01318-100

Citations, Manuals and MSDS Available upon request.

Background: The peptidase M14 family of carboxypeptidases (CPs) are involved in various functions throughout the body which include digestion of food and biosynthesis of peptides that function in intercellular signaling. CCP2 (cytosolic carboxypeptidase 2), also known as AGBL2 (ATP/GTP binding protein-like 2), is a 902 amino acid cytoplasmic protein belonging to the peptidase M14 family. CCP2 is considered a metallocarboxypeptidase that may play a role in the processing of tubulin. CCP2 binds one zinc ion per subunit as a cofactor and exists as three alternatively spliced isoforms. The gene encoding CCP2 is located on human chromosome 11p11.2. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

Research Areas: Signal Transduction

Target Protein: AGBL2

Applications: WB, IHC-p, ELISA

Reactivity: Human, Mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: CCP2 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 104176

UniProt Accession: Human: Q5U5Z8; Mouse: Q8CDK2

Synonyms: AGBL2; CCP2; Cytosolic carboxypeptidase 2; ATP/GTP-binding protein-like 2

GeneID: Human: 79841; Mouse: 271813

Research Use Only