CD105 Monoclonal Antibody - BT-MCA3999

CD105 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3999-50, BT-MCA3999-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research Areas: Others

Target Protein: CD105

Applications: WB, IHC, FCM

Clonality: Monoclonal

Clone ID: 2B2H2

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: CD105

Immunogen: Purified recombinant fragment of human CD105 (AA: extra 342-586) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 70.6kDa

UniProt Accession: P17813

Synonyms: ENG, END, HHT1, ORW1

GeneID: 2022

Research Use Only