CD105 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA22908-50, RA22908-100
Citations, Manuals and MSDS Available upon request.
Background: endoglin (ENG) Homo sapiens This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: WB 1:500-2000, ELISA (peptide) 1:5000-20000
Alternative Names: Endoglin (CD antigen CD105)
Applications: WB; ELISA
Species Cross-Reactivity: Human; Rat; Mouse
GeneID (Human): 2022
Protein MW (KDa): 85
SWISS: P17813
Source: Rabbit
Research Use Only