Product Description

CD107a/LAMP1 Polyclonal Antibody

Catalogue Numbers: NCP0245P-50, NCP0245P-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Swiss-Prot: P11279

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB: 1:1000~1:2000

Background: Lysosome-associated membrane protein 1 and 2 (LAMP1 and LAMP2) are two abundant lysosomal membrane proteins. Both are transmembrane proteins and are heavily glycosylated at the amino-terminal luminal side of the lysosomal inner leaflet, which protects the proteins from proteolysis. The carboxy terminus of LAMP1 is exposed to the cytoplasm and contains a tyrosine sorting motif that targets LAMP to lysosomal membranes. LAMP1 and LAMP2 are 37% homologous in their protein sequences. Both LAMP1 and LAMP2 are involved in regulating lysosomal motility during lysosome-phagosome fusion and cholesterol trafficking.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CD107a/LAMP1 polyclonal antibody detects endogenous levels of CD107a/LAMP1 protein.

Extra Notes: Western blot (WB) analysis of CD107a/LAMP1 polyclonal antibody at 1:1000 dilution
Lane1:The Stomach tissue lysate of Mouse(30ug)
Lane2:The Kidney tissue lysate of Rat(30ug)
Lane3:HCT116 whole cell lysate(30ug)
Lane4:HEK293T whole cell lysate(30ug)

Bioworld Molecular Weight: ~ 95 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Lysosome-associated membrane glycoprotein 1; LAMP-1; Lysosome-associated membrane protein 1; CD107 antigen-like family member A; CD107a; LAMP1

Immunogen: Synthetic peptide, corresponding to Human CD107a/LAMP1.

Conjugate: Unconjugated

Modification: Unmodified