Product Description

CD112/NECTIN2 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: NCP0248P-50, NCP0248P-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Swiss-Prot: Q92692

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IF

All Applications: WB: 1:2000~1:5000
IF 1:50~1:200

Background: Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive .Probable cell adhesion protein .

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CD112/NECTIN2 polyclonal antibody detects endogenous levels of CD112/NECTIN2 protein.

Bioworld Molecular Weight: ~ 60-70 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of CD112/NECTIN2 polyclonal antibody at 1:2000 dilution
Lane 1: CT-26 whole cell lysate (30ug)
Lane 2: H1792 whole cell lysate (20ug)
Lane 3: HEK293T whole cell lysate (20ug), Immunofluorescence analysis of HEK293T cells using CD112/NECTIN2 pAb at dilution of 1:200.

Alternative Name: Nectin-2; Herpes virus entry mediator B; Herpesvirus entry mediator B; HveB; Nectin cell adhesion molecule 2; Poliovirus receptor-related protein 2; CD112

Immunogen: Recombinant protein of human CD112/NECTIN2.

Conjugate: Unconjugated

Modification: Unmodified