Product Description

CD113/NECTIN3  Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: NCP0249P-50, NCP0249P-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecμles such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regμlation of PVR from the cell surface, resμlting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.

Category: Primary Antibody

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: IF

Alternate Names: Nectin-3, CDw113, Nectin cell adhesion molecμle 3, Poliovirus receptor-related protein 3, CD113, NECTIN3 , PRR3, PVRL3

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Recombinant protein of human CD113/NECTIN3.

Dilution: IF: 1:100~1:500

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CD113/NECTIN3 polyclonal antibody detects endogenous levels of CD113/NECTIN3 protein.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9NQS3

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Research Use Only