CD113 Polyclonal Antibody-BS67477

CD113 Polyclonal Antibody

Catalogue Numbers: BS67477-50, BS67477-100

Sizes: 50µl, 100µl

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: Q9NQS3

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with NECTIN2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.

Purification and Purity: The antibody was purified by immunogen affinity chromatography.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of CD113 protein.

Extra Notes: Western blot analysis of CD113 expression in Hela (A), A549 (B), C6 (C), AML12 (D) whole cell lysates.

Bioworld Molecular Weight: ~ 95 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: PRR3; Poliovirus receptor-related protein 3; CDw113; Nectin-3; CD113

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD113. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified