CD116 Polyclonal Antibody-BS62545

CD116 Polyclonal Antibody

Catalogue Numbers: BS62545-50, BS62545-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P15509

Host: Rabbit

Reactivity: Human, Rat

Applications: WB

All Applications: WB:1:500~1:1000

Background: The human IL-3, IL-5 and GM-CSF receptors are each composed of both unique a subunits and a common β subunit. The a subunits are low affinity ligand binding proteins while the β subunits do not themselves bind ligand, but are required for high affinity binding by the a subunits. In contrast, the mouse IL-3 receptor has two distinct β subunits, one that functions only in IL-3 mediated cell signaling and a second that is shared with IL-5 and GM-CSF. The murine β-subunits are 91% homologous at the amino acid level but only 56% homologous to the human β subunit. Although neither the murine nor the human β subunit contains tyrosine kinase domains, both activate tyrosine phosphorylation mediated signaling pathways.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CD116 polyclonal antibody detects endogenous levels of CD116 protein.

Extra Notes: Western blot (WB) analysis of CD116 polyclonal antibody at 1:500 dilution
LaneA:The Lung tissue lysate of Rat

Bioworld Molecular Weight: ~ 46 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: CD116; CD116 antigen; CDw116; Colony stimulating factor 2 receptor alpha chain; CSF 2R; CSF2R; CSF2RA; CSF2RAX; CSF2RAY; CSF2RX; CSF2RY; GM CSF R alpha; GM CSF receptor alpha subunit; GM-CSF-R-alpha; GMCSFR; GMCSFR-alpha; GMR-alpha; Granulocyte-macrophage colony-stimulating factor receptor subunit alpha

Immunogen: Synthetic peptide, corresponding to Human CD116.

Conjugate: Unconjugated

Modification: Unmodified