CD11b Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA22918-50, RA22918-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: integrin subunit alpha M (ITGAM) Homo sapiens This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009], Reactivity: Human, Rat, Mouse Host: Rabbit Applications: IHC-p, IF (paraffin section), mult-IHC, ELISA Alternate Names: Integrin alpha-M (CD11 antigen-like family member B;CR-3 alpha chain;Cell surface glycoprotein MAC-1 subunit alpha;Leukocyte adhesion receptor MO1;Neutrophil adherence receptor;CD antigen CD11b) Clonality: Polyclonal Dilution: IHC-p 1:50-200, ELISA 1:10000-20000 Storage: -20°C/1 year Human Gene ID: 3684 Human SwissProt Number: P11215 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only