Product Description

CD11c Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB65814-50, MB65814-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: CD11c (integrin αX, ITGAX) is a transmembrane glycoprotein that forms an α/β heterodimer with CD18 (integrin β2), which interacts with a variety of extracellμlar matrix molecμles and cell surface proteins. CD11c is primarily used as a dendritic cell marker. Dendritic cells can be classified into two major types: CD11c+ conventional dendritic cells that specialize in antigen presentation, and CD11c- plasmacytoid dendritic cells that specialize in type I interferon production. CD11c expression has also been observed on activated NK cells, subsets of B cells, monocytes, granμlocytes, and some B cell malignancies including hairy cell leukemia.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: IF, FC

Alternate Names: CD11C, Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150, 95 alpha chain, Leukocyte adhesion receptor p150, 95, CD11c

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Native purified human CD11c

Dilution: IF (1/50 - 1/200)

Purification: The monoclonal antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Recognizes human CD11c

Molecular Weight: ~ 127 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P20702

Product: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, and 0.02% sodium azide.

Research Use Only