CD125 Polyclonal Antibody-NCP0256P

CD125 Polyclonal Antibody

Catalogue Numbers: NCP0256P-50, NCP0256P-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Swiss-Prot: Q01344

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB

All Applications: WB: 1:2000~1:5000

Background: Cell surface receptor that plays an important role in the survival, differentiation, and chemotaxis of eosinophils .Acts by forming an heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5.In unstimulated conditions, interacts constitutively with JAK2. Heterodimeric receptor activation leads to JAK2 stimulation and subsequent activation of the JAK-STAT pathway .

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CD125 polyclonal antibody detects endogenous levels of CD125 protein.

Extra Notes: Western blot (WB) analysis of CD125 polyclonal antibody at 1:2000 dilution
Lane1:EC9706 cell membrane lysate(25ug)
Lane2:MCF-7 cell membrane lysate(25ug)

Bioworld Molecular Weight: ~ 60 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Interleukin-5 receptor subunit alpha; IL-5 receptor subunit alpha; IL-5R subunit alpha; IL-5R-alpha; IL-5RA; CDw125; CD125

Immunogen: Recombinant protein of human CD125.

Conjugate: Unconjugated

Modification: Unmodified