Product Description

CD130 Polyclonal Antibody

Product: PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Sizes: 50µl, 100µl

Catalogue Numbers: BZ17062-50, BZ17062-100

Swiss-Prot: P40189

Host: Rabbit

CD130 Polyclonal Antibody-BZ17062

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse

Applications: WB, IHC-P

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100

Background: The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize IL6ST for initiating signal transmission. Binding of IL6 to IL6R induces IL6ST homodimerization and formation of a high-affinity receptor complex, which activates the intracellular JAK-MAPK and JAK-STAT3 signaling pathways.

Purification and Purity: Affinity Purified

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 104 kDa; Observed MW: 130-140kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of CD130 in 293T, COLOLysates using CD130 antibody., Immunohistochemistry analysis of paraffin-embedded human brain using CD130 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.Sample withBlocking peptide on the right.

Alternative Name: Interleukin-6 receptor subunit beta ,IL-6 receptor subunit beta,IL-6R subunit beta,IL-6R-beta, IL-6RB,CDw130

Immunogen: A synthesized peptide derived from human CD130/gp130

Modification: Unmodified

Conjugate: Unconjugated