Product Description

CD131 Polyclonal Antibody

Catalogue Numbers: NCP0259P-50, NCP0259P-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Swiss-Prot: P32927

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB

All Applications: WB: 1:1000~1:2000

Background: The common beta-chain (beta-c) of the granulocyte macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3) and IL-5 receptors is the major signaling subunit of these receptors, coupling ligand binding to multiple biological activities. Tyrosine phosphorylation of cytokine receptor common beta-chain is one of the first events in GM-CSF, IL-3 and IL-5 receptor activation and in signaling initiation. Serine phosphorylation within the 14-3-3 binding sequence of the common beta-chain is also involved in GM-CSF, IL-3 and IL-5 receptor-specific functions.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CD131 polyclonal antibody detects endogenous levels of CD131 protein.

Extra Notes: Western blot (WB) analysis of CD131 polyclonal antibody at 1:1000 dilution
Lane1:Jurkat whole cell lysate(30ug)
Lane2:The Liver tissue lysate of Mouse(30ug)

Bioworld Molecular Weight: ~ 130 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Cytokine receptor common subunit beta; CDw131; GM-CSF/IL-3/IL-5 receptor common beta subunit; CD131; CSF2RB; IL3RB; IL5RB

Immunogen: Recombinant protein of human CD131.

Conjugate: Unconjugated

Modification: Unmodified