Product Description

CD131 Recombinant Protein

Sizes: 500μg, 1mg

Catalogue Numbers: NCP0259-500, NCP0259-1000

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The common beta-chain (beta-c) of the granμlocyte macrophage colony-stimμlating factor (GM-CSF), interleukin-3 (IL-3) and IL-5 receptors is the major signaling subunit of these receptors, coupling ligand binding to mμltiple biological activities. Tyrosine phosphorylation of cytokine receptor common beta-chain is one of the first events in GM-CSF, IL-3 and IL-5 receptor activation and in signaling initiation. Serine phosphorylation within the 14-3-3 binding sequence of the common beta-chain is also involved in GM-CSF, IL-3 and IL-5 receptor-specific functions.

Category: Protein

Host: E. coli

Purification and Purity: Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE).

Molecular Weight: ~47kDa

Solubility: PBS, 4M Urea, PH7.4

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Restriction Sites: NdeI-XhoI

SwissProt: P32927

Tag: His-tag

Amino Acid Sequence: TGGGAACGTAGTCTGGCAGGTGCCGAAGAAACCATTCCGCTGCAGACCCTGCGCTGTTATAATGATTATACCAGTCATATTACCTGCCGCTGGGCAGATACCCAGGATGCCCAGCGTCTGGTTAATGTTACCCTGATTCGCCGTGTGAATGAAGATCTGCTGGAACCGGTGAGTTGCGATCTGAGCGATGATATGCCGTGGAGCGCCTGTCCGCATCCGCGTTGTGTGCCGCGCCGTTGCGTTATTCCGTGCCAGAGCTTCGTTGTTACCGATGTTGATTACTTCAGCTTCCAGCCGGATCGTCCGCTGGGTACCCGTCTGACCGTGACCCTGACCCAGCATGTGCAGCCGCCGGAACCGCGTGATCTGCAGATTAGTACCGATCAGGATCACTTCCTGCTGACCTGGAGTGTGGCACTGGGCAGCCCGCAGAGCCATTGGCTGAGTCCGGGCGATCTGGAATTCGAAGTGGTGTATAAACGTCTGCAGGATAGTTGGGAAGATGCAGCCATTCTGCTGAGTAATACCAGCCAGGCAACCCTGGGCCCGGAACATCTGATGCCGAGCAGTACCTATGTTGCCCGTGTTCGTACCCGCCTGGCCCCGGGTAGCCGTCTTAGCGGTCGCCCTAGTAAATGGAGCCCGGAAGTGTGTTGGGATAGTCAGCCGGGCGATGAAGCACAGCCGCAGAATCTGGAATGCTTCTTCGATGGCGCAGCCGTGCTGAGCTGTAGCTGGGAAGTGCGTAAAGAAGTGGCCAGCAGTGTTAGCTTCGGCCTGTTCTATAAACCGAGTCCGGATGCCGGTGAAGAAGAATGCAGCCCGGTGCTGCGCGAAGGTCTGGGTAGTCTGCATACCCGTCATCATTGCCAGATTCCGGTTCCGGATCCGGCCACCCATGGTCAGTATATTGTGAGTGTTCAGCCGCGCCGCGCCGAAAAACATATTAAAAGTAGTGTGAATATCCAGATGGCACCGCCGAGCCTGAATGTGACCAAAGATGGTGATAGTTATAGCCTGCGTTGGGAAACCATGAAAATGCGCTATGAACATATTGATCATACCTTCGAAATCCAGTATCGCAAAGATACCGCAACCTGGAAAGATAGCAAAACCGAAACCTTACAGAATGCACATAGTATGGCCCTGCCGGCCCTGGAACCGAGTACCCGTTATTGGGCCCGCGTTCGCGTGCGTACCAGCCGTACCGGTTATAATGGTATCTGGAGCGAATGGAGTGAAGCCCGCAGTTGGGATACCGAAAGCGTTCTGCCGATGTGG

Expression Vector: pet-22b(+)

Research Use Only