CD141 rabbit pAb - ES7386

CD141 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7386-50, ES7386-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008],

Alternate Name: THBD; THRM; Thrombomodulin; TM; Fetomodulin; CD antigen CD141

Source: Rabbit

Applications: WB; ELISA

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human THBD. AA range:526-575

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 60kD

Human Gene ID: 7056

Human SWISS Prot NO: P07204

Subcellular Location: Membrane; Single-pass type I membrane protein.

Research Use Only