Product Description

CD141 Recombinant Protein

Catalogue Number: NCP0266-500, NCP0266-1000

Sizes: 500ug, 1mg

Swiss-Prot: P07204

Host: E.coli

Tag: His-tag

AA Sequence: GCACCTGCAGAACCGCAGCCGGGTGGCAGTCAGTGTGTGGAACATGATTGCTTCGCCCTGTATCCGGGCCCGGCAACCTTCCTGAATGCAAGTCAGATCTGTGATGGTCTGCGTGGCCATCTGATGACCGTTCGTAGTAGTGTGGCCGCCGATGTGATTAGTCTGCTGCTGAATGGTGATGGCGGTGTTGGCCGTCGTCGCCTGTGGATTGGCCTGCAGCTGCCGCCGGGCTGTGGCGACCCTAAACGTCTGGGCCCGCTGCGTGGCTTCCAGTGGGTGACCGGCGATAATAATACCAGCTATAGCCGCTGGGCACGCCTGGATCTGAATGGCGCCCCGCTGTGTGGCCCGCTGTGCGTGGCAGTGAGCGCCGCAGAAGCCACCGTGCCGAGTGAACCGATCTGGGAAGAACAGCAGTGTGAAGTTAAAGCAGATGGCTTCCTGTGCGAATTCCACTTCCCGGCAACCTGTCGCCCGCTGGCAGTTGAACCGGGTGCCGCAGCCGCCGCTGTTAGTATTACCTATGGCACCCCGTTCGCCGCCCGTGGTGCCGACTTCCAGGCCTTACCGGTGGGTAGCAGCGCCGCAGTGGCACCTCTGGGCCTGCAGTTAATGTGTACCGCACCGCCGGGTGCCGTTCAGGGTCATTGGGCCCGTGAAGCACCGGGCGCATGGGATTGTAGTGTTGAAAATGGTGGTTGCGAACATGCATGCAATGCAATTCCGGGTGCCCCGCGCTGTCAGTGCCCGGCAGGTGCAGCTCTGCAGGCCGATGGCCGTAGTTGCACCGCAAGCGCCACCCAGAGCTGCAATGATCTGTGTGAACACTTCTGTGTGCCGAATCCGGATCAGCCGGGTAGCTATAGTTGTATGTGCGAAACCGGTTATCGTCTGGCCGCAGATCAGCATCGCTGCGAAGATGTTGATGATTGTATTCTGGAACCGAGCCCGTGTCCGCAGCGTTGCGTTAATACCCAGGGCGGCTTCGAATGCCATTGCTATCCGAATTATGATCTGGTGGATGGTGAATGCGTTGAACCGGTGGATCCGTGCTTCCGTGCAAATTGCGAATATCAGTGTCAGCCGCTGAATCAGACCAGCTATCTGTGCGTGTGTGCCGAAGGCTTCGCACCGATTCCGCATGAACCGCATCGCTGCCAGATGTTCTGCAATCAGACCGCCTGTCCGGCAGATTGCGATCCGAATACCCAGGCAAGCTGCGAATGCCCGGAAGGCTATATTCTGGATGATGGCTTCATCTGTACCGATATTGATGAATGTGAAAATGGCGGCTTCTGCAGCGGCGTGTGTCATAATCTGCCGGGTACCTTCGAATGTATCTGTGGCCCGGATAGCGCACTGGCACGCCATATTGGTACCGATTGTGATAGTGGTAAAGTGGATGGTGGTGATAGTGGCAGCGGTGAACCGCCGCCGAGCCCTACACCGGGTAGTACCCTGACCCCGCCGGCAGTGGGTCTGGTTCATAGC

Restriction Sites: NdeI-XhoI

Background: CD141/Thrombomodulin (TM, THBD, BDCA-3) is an integral membrane protein expressed on the surface of endothelial cells. Acting as a cofactor with Thrombin, CD141/Thrombomodulin activates and initiates the Protein C anticoagulant pathway. CD141/Thrombomodulin is expressed by a small subset of human CD11c+ myeloid dendritic cells. These CD141+XCR1+ dendritic cells cross-present antigens to naïve CD8+ T cells, priming them to become activated cytotoxic CD8+ T cells.

Soluble: PBS, 4M Urea, PH7.4

Purification and Purity: Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Expression Vector: pet-22b(+)

BioWorld Molecular Weight: ~66kDa

Notes: For research use only, not for use in diagnostic procedure.