CD152 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA22934-50, RA22934-100
Citations, Manuals and MSDS Available upon request.
Background: cytotoxic T-lymphocyte associated protein 4 (CTLA4) Homo sapiens This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: IHC-p 1:50-200, ELISA 1:10000-20000
Alternative Names: Cytotoxic T-lymphocyte protein 4 (Cytotoxic T-lymphocyte-associated antigen 4;CTLA-4;CD antigen CD152)
Applications: IHC-p; IF (paraffin section) ; ELISA
Species Cross-Reactivity: Human; Rat; Mouse
GeneID (Human): 1493
SWISS: P16410
Source: Rabbit
Research Use Only