CD156c Polyclonal Antibody - E-AB-70180

CD156c Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-70180-60, E-AB-70180-120, E-AB-70180-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD156c

Target Synonym: A disintegrin and metalloprotease domain 10; A disintegrin and metalloproteinase domain 10; AD 10; AD10; AD18; ADA10; ADAM 10; ADAM metallopeptidase domain 10; ADAM10; CD 156c; CD156c; CD156c antigen; CDw156; disintegrin and metalloproteinase domain containing protein 10; Disintegrin and metalloproteinase domain-containing protein 10; HsT 18717; HsT18717; Kuz; Kuzbanian; Kuzbanian protein homolog; Kuzbanian; Drosophila; homolog of; MADM; Mammalian disintegrin metalloprotease; Mammalian disintegrin-metalloprotease; RAK

Research Areas: Cancer, Cell Biology, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O14672,O35598,Q10743

Background: Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Cleaves the membrane-bound precursor of TNF-alpha at '76-Ala-|-Val-77' to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP).

Concentration: 210 μg/mL

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse ADAM10

Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:1000

Calculated MW: 84kDa

Observed MW: 95kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only