Product Description

CD159c Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS67365-50, BS67365-100

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: P26717

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB,

All Applications: WB (1/500 - 1/1000)

Background: Immune activating receptor involved in self-nonself discrimination. In complex with KLRD1 on cytotoxic lymphocyte subsets, recognizes non-classical major histocompatibility (MHC) class Ib HLA-E loaded with signal sequence-derived peptides from non-classical MHC class Ib HLA-G molecules, likely playing a role in the generation and effector functions of adaptive natural killer (NK) cells and in maternal-fetal tolerance during pregnancy.

Purification and Purity: The antibody was purified by immunogen affinity chromatography.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of CD159c protein.

Bioworld Molecular Weight: ~ 27 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of CD159c expression in rat spleen (A), mouse spleen (B) whole cell lysates.

Alternative Name: NKG2C; NKG2-C type II integral membrane protein; CD159 antigen-like family member C; NK cell receptor C; NKG2-C-activating NK receptor; CD159c

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CD159c. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified