Product Description

CD16/CD32 Rat Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB65856-50, MB65856-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Receptor for the Fc region of complexed immunoglobμlins gamma. Low affinity receptor. Involved in a variety of effector and regμlatory functions such as phagocytosis of antigen-antibody complexes from the circμlation and modμlation of antibody production by B-cells. Isoform IIB1 and isoform IIB1' form caps but fail to mediate endocytosis or phagocytosis. Isoform IIB2 can mediate the endocytosis of soluble immune complexes via clathrin-coated pits. Isoform IIB1 and isoform IIB2 can down-regμlate B-cell, T-cell, and mast cell activation when coaggregated to B-cell receptors for AG (BCR), T-cell receptors for AG (TCR), and Fc receptors, respectively.

Category: Primary Antibody

Reactivity: Mouse

Host: Rat

Applications: IF, FC

Alternate Names: CD32, FCG2, IGFR2, Low affinity immunoglobμlin gamma Fc region receptor II-b, IgG Fc receptor II-b, CDw32, Fc-gamma RII-b, Fc-gamma-RIIb, FcRII-b, CD32

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Sorted pre-B cells

Dilution: IF (1/50 - 1/200)

Purification: The monoclonal antibody was affinity-purified from Rat antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Recognizes mouse CD16/CD32

Molecular Weight: ~ 36 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P08101, P08508

Product: Rat IgG2a lambda. Liquid in PBS, pH 7.3, and 0.02% sodium azide.

Research Use Only