CD16/CD32 Rat Monoclonal Antibody-MB65856

CD16/CD32 Rat Monoclonal Antibody

Catalogue Numbers:MB65856-50, MB65856-100

Product: Rat IgG2a lambda. Liquid in PBS, pH 7.3, and 0.02% sodium azide.

Swiss-Prot: P08101; P08508

Host: Rat

Reactivity: Mouse

Applications: IF, FC

All Applications: IF (1/50 - 1/200)

Background: Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of antigen-antibody complexes from the circulation and modulation of antibody production by B-cells. Isoform IIB1 and isoform IIB1' form caps but fail to mediate endocytosis or phagocytosis. Isoform IIB2 can mediate the endocytosis of soluble immune complexes via clathrin-coated pits. Isoform IIB1 and isoform IIB2 can down-regulate B-cell, T-cell, and mast cell activation when coaggregated to B-cell receptors for AG (BCR), T-cell receptors for AG (TCR), and Fc receptors, respectively.

Purification and Purity: The monoclonal antibody was affinity-purified from Rat antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Bioworld Molecular Weight: ~ 36 kDa

Specificity: Recognizes mouse CD16/CD32

Note: For research use only, not for use in diagnostic procedure.
Alternative Name: CD32; FCG2; IGFR2; Low affinity immunoglobulin gamma Fc region receptor II-b; IgG Fc receptor II-b; CDw32; Fc-gamma RII-b; Fc-gamma-RIIb; FcRII-b; CD32

Immunogen: Sorted pre-B cells

Conjugate: Unconjugated

Modification: Unmodified