CD16 Monoclonal Antibody (Q32) - RA10912

CD16 Monoclonal Antibody (Q32)

Size: 50μL, 100μL

Catalogue Numbers: RA10912-50, RA10912-100

Citations, Manuals and MSDS Available upon request.

Background: Fc fragment of IgG receptor IIIa (FCGR3A) Homo sapiens This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq,

Condition: PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Storage Instructions: -20°C/1 year

Applications: WB; IHC-p; IF (paraffin section) ;

Species Cross-Reactivity: Human

GeneID (Human): 2214/2215

Protein MW (KDa): 45

SWISS: P08637/O75015

Source: Mouse

Research Use Only