Product Description

CD16 Monoclonal Antibody (Q32)

Sizes: 50μL, 100μL

Catalogue Numbers: RA10912-50, RA10912-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Fc fragment of IgG receptor IIIa (FCGR3A) Homo sapiens This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq,

Reactivity: Human

Host: Mouse

Applications: WB, IHC-p, IF(paraffin section),

Clonality: Monoclonal

Dilution: WB: 1:1000 IHC 1:50-300

Storage: -20°C/1 year

Condition: PBS, pH 7.4, containing 0.5% BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Human Gene ID: 2214/2215

Protein Molecular Weight（KDa): 45

Molecular Weight: 45

Research Use Only