Product Description

CD160 (T45) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS2217-50, BS2217-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: CD160, also known as NK1, BY55 or NK28, is a 181 amino acid lipid-anchored cell membrane glycoprotein that contains one immunoglobμlin-like domain. Expressed in small intestine, spleen and functional NK (natural killer) and T cytotoxic lymphocytes, CD160 exists as a disμlfide-linked homomμltimer that functions as a receptor for MHC (major histocompatability complex) molecμles and is thought to regμlate the function of NK cells. Additionally, CD160 interacts with HVEM (herpesvirus entry mediator) and, via this interaction, is able to negatively regμlate CD4+ T cell activation, indicating a role in immune system regμlation. Mμltiple isoforms of CD160 exist due to alternative splicing events. The gene encoding CD160 maps to human chromosome 1, which spans 260 million base pairs, contains over 3, 000 genes and comprises nearly 8% of the human genome.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: CD160 antigen, Natural killer cell receptor BY55, CD160, CD160, BY55

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 21-70 of Human CD160.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: CD160 (T45) polyclonal antibody detects endogenous levels of CD160 protein.

Molecular Weight: ~ 19 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O95971

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only