CD162 Polyclonal Antibody-BS65570

CD162 Polyclonal Antibody Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Sizes: 50µl, 100µl Catalogue Numbers: BS65570-50, BS65570-100 Swiss-Prot: Q14242 Host: Rabbit CD162 Polyclonal Antibody-BS65570 Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. Reactivity: Human Applications: WB, All Applications: WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. Background: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]. Purification and Purity: affinity purified by Protein A Specificity: CD162 polyclonal Antibody detects endogenous levels of CD162 protein. Bioworld Molecular Weight: ~41kDa Note: For research use only, not for use in diagnostic procedure. Extra Notes: Anti-CD162 at 1/500 dilution, Anti-CD162 at 1/500 dilution Alternative Name: CD 162; CD162; CD162 antigen; CLA; Cutaneous lymphocyte associated associated antigen; P selectin glycoprotein ligand 1; P selectin glycoprotein ligand 1 precursor; P-selectin glycoprotein ligand 1; PSGL 1; PSGL-1; PSGL1; Selectin P ligand; SELPL_HUMAN; SELPLG. Immunogen: KLH conjugated synthetic peptide derived from human PSGL-1:251-350/412 Modification: Unmodified Conjugate: Unconjugated