CD162 Polyclonal Antibody Sizes: 50μl, 100μl Catalogue Numbers: BS65570-50, BS65570-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecμles P-, E- and L- selectin expressed on myeloid cells and stimμlated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sμlfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing resμlts in mμltiple transcript variants.[provided by RefSeq, Apr 2011]. Category: Primary Antibody Reactivity: Human Host: Rabbit Applications: WB Alternate Names: CD 162, CD162, CD162 antigen, CLA, Cutaneous lymphocyte associated associated antigen, P selectin glycoprotein ligand 1, P selectin glycoprotein ligand 1 precursor, P-selectin glycoprotein ligand 1, PSGL 1, PSGL-1, PSGL1, Selectin P ligand, SELPL_HUMAN, SELPLG. Clonality: Polyclonal Conjugate: Unconjugated Modification: Unmodification Immunogen: KLH conjugated synthetic peptide derived from human PSGL-1:251-350/412 Dilution: WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations shoμld be determined by the end user. Purification: affinity purified by Protein A Specificity: CD162 polyclonal Antibody detects endogenous levels of CD162 protein. Molecular Weight: ~41kDa Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. SwissProt: Q14242 Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Research Use Only