CD166 rabbit pAb - ES4126

CD166 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4126-50, ES4126-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2011],

Alternate Name: ALCAM; MEMD; CD166 antigen; Activated leukocyte cell adhesion molecule; CD166

Source: Rabbit

Applications: IF; WB; ELISA

Dilution: IF: 1:50-200 Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human ALCAM. AA range:481-530

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 65kD

Human Gene ID: 214

Human SWISS Prot NO: Q13740

Subcellular Location: Cell membrane; Single-pass type I membrane protein. Cell projection, axon. Cell projection, dendrite. Detected at the immunological synapse, i.e, at the contact zone between antigen-presenting dendritic cells and T-cells (PubMed:15294938, PubMed:16352806). Colocalizes with CD6 and the TCR/CD3 complex at the immunological synapse (PubMed:15294938).; [Isoform 3]: Secreted.

Research Use Only