Product Description

CD167a Recombinant Protein

Sizes: 500μg, 1mg

Catalogue Numbers: NCP0289-500, NCP0289-1000

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The discoidin domain receptors (DDRs) are receptor tyrosine kinases with a discoidin homology repeat in their extracellμlar domains, activated by binding to extracellμlar matrix collagens. So far, two mammalian DDRs have been identified: DDR1 and DDR2. They are widely expressed in human tissues and may have roles in smooth muscle cell-mediated collagen remodeling. Research studies have implicated aberrant expression and signaling of DDRs in human diseases related to increased matrix degradation and remodeling, such as cardiovascμlar disease, liver fibrosis, and tumor invasion.

Category: Protein

Host: E. coli

Purification and Purity: Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE).

Molecular Weight: ~44kDa

Solubility: PBS, 4M Urea, PH7.4

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Restriction Sites: NdeI-XhoI

SwissProt: Q08345

Tag: His-tag

Amino Acid Sequence: GATATGAAGGGTCACTTCGATCCGGCCAAATGCCGCTATGCACTGGGTATGCAGGATCGTACCATTCCGGATAGTGATATTAGCGCAAGTAGCAGCTGGAGTGATAGCACCGCAGCACGTCATAGTCGTCTGGAAAGTAGCGATGGCGATGGTGCCTGGTGCCCGGCCGGTTCAGTGTTCCCGAAAGAAGAAGAATATCTGCAGGTTGATCTGCAGCGTCTGCATCTGGTGGCACTGGTTGGTACCCAGGGCCGTCATGCCGGTGGTCTGGGCAAAGAATTCAGTCGCAGTTATCGCCTGCGTTATAGCCGTGATGGTCGCCGTTGGATGGGTTGGAAAGATCGTTGGGGCCAGGAAGTGATTAGTGGTAATGAAGATCCGGAAGGTGTTGTTCTGAAAGATCTGGGTCCGCCGATGGTTGCACGCCTGGTTCGCTTCTATCCGCGTGCAGATCGCGTGATGAGTGTGTGTCTGCGCGTGGAACTGTATGGTTGCCTGTGGCGCGATGGTCTGCTGAGTTATACCGCACCGGTGGGCCAGACCATGTATCTGAGTGAAGCCGTGTATCTGAATGATAGTACCTATGATGGTCATACCGTTGGTGGTCTGCAGTATGGTGGCCTGGGTCAGCTGGCCGATGGTGTTGTGGGCCTGGATGACTTCCGTAAAAGCCAGGAACTGCGCGTGTGGCCGGGCTATGATTATGTTGGTTGGAGTAATCATAGCTTCAGCAGCGGTTATGTTGAAATGGAATTCGAATTCGATCGTCTGCGCGCCTTCCAGGCCATGCAGGTGCATTGTAATAATATGCATACCCTGGGTGCCCGTCTGCCGGGCGGTGTTGAATGCCGCTTCCGCCGCGGTCCGGCAATGGCATGGGAAGGTGAACCGATGCGTCATAATCTGGGTGGTAATCTGGGCGATCCGCGCGCACGTGCAGTTAGTGTGCCGCTGGGCGGCCGTGTGGCACGCTTCTTACAGTGTCGCTTCCTGTTCGCCGGTCCGTGGCTGCTGTTCAGCGAAATTAGCTTCATTAGCGATGTGGTGAATAATAGTAGCCCGGCCCTGGGCGGCACCTTCCCTCCTGCACCTTGGTGGCCGCCGGGTCCTCCTCCTACCAACTTCAGTAGTCTGGAACTGGAACCGCGTGGTCAGCAGCCGGTGGCAAAAGCCGAAGGCAGTCCGACCGCA

Expression Vector: pet-22b(+)

Research Use Only