Product Description

CD169 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-70160-60, E-AB-70160-120, E-AB-70160-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD169

Target Synonym: CD169; CD169 antigen; dJ1009E24.1; DKFZp667F058; FLJ00051; FLJ00055; FLJ00073; FLJ00411; FLJ32150; Sialic acid binding Ig like lectin 1; sialic acid binding Ig-like lectin 1; sialoadhesin; Sialic acid binding immunoglobulin like lectin 1; Sialic acid-binding Ig-like lectin 1; Sialoadhesin; Siglec 1; Siglec-1; Siglec1; SN; SN

Research Areas: Cancer, Immunology, Microbiology

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9BZZ2,Q62230

Background: This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined.SIGLEC1 (Sialic Acid Binding Ig Like Lectin 1) is a Protein Coding gene. Diseases associated with SIGLEC1 include Proliferative Glomerulonephritis and Diffuse Cutaneous Systemic Sclerosis. Among its related pathways are Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell and Innate Immune System. GO annotations related to this gene include carbohydrate binding. An important paralog of this gene is CD22.

Concentration: 1.4 mg/mL

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse CD169

Buffer: PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification Method: Affinity purification

Dilution: IHC 1:200-1:800

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only