CD18 Polyclonal Antibody-BS90220

CD18 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90220-50, BS90220-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P05107(Human)

Host: Rabbit

Reactivity: Human

Applications: WB IP

All Applications: WB:1:500-1:1,000
IP:1:10-1:50

Background: Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of CD18 on Jurkat cellsLysates using anti-CD18 antibody at 1/500 dilution.

Bioworld Molecular Weight: 95 kDa

Specificity: CD18 polyclonal antibody detects endogenous levels of CD18 protein.

Alternative Name: ITGB2, 95 subunit beta, Beta 2 (antigen CD18 (p95), CD 18, CD18, Cell surface adhesion glycoprotein LFA 1/CR3/P150, 959 beta subunit precursor), Cell surface adhesion glycoproteins LFA 1/CR3/p150, 95 subunit beta, Cell surface adhesion glycoproteins LFA-1/CR3/p150, Complement component 3 receptor 3 and 4 subunit, Complement receptor C3 beta subunit, Complement receptor C3 subunit beta, Integrin beta 2, Integrin beta chain beta 2, Integrin beta-2 (ITGB2), Integrin beta-2, Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit), ITB2, ITGB2, LAD, LCAMB, Leukocyte associated antigens CD18/11A, CD18/11B, CD18/11C, Leukocyte cell adhesion molecule CD18, LFA 1, LFA1, Lymphocyte function associated antigen 1 (LFA1), Lymphocyte function associated antigen 1, MAC 1, MAC1, Macrophage antigen 1 (mac1) beta, MF17, MFI7, OTTHUMP00000115278, OTTHUMP00000115279, OTTHUMP00000115280, OTTHUMP00000115281, OTTHUMP00000115282,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified