Product Description

CD1D Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS6546-50, BS6546-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P15813

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB IF

All Applications: WB 1:500 - 1:2000
IF 1:50 - 1:200

Background: The CD1 multigene family encodes five forms of the CD1 T cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. CD1 antigens are associated with β-2-Microglobulin and expressed on cortical thymocytes, Langerhans cells, a B cell subset and some dendritic cells. Adaptor protein complexes and CD1-associated chaperones control CD1 trafficking and the development and activation of CD1-restricted T cells. CD1D is present on human intestinal epithelial cells (IEC) and exists as a β-2-Microglobulin-independent nonglycosylated form or a β-2-Microglobulin-dependent glycosylated form.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CD1D polyclonal antibody detects endogenous levels of CD1D protein.

Bioworld Molecular Weight: ~ 37 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot analysis of CD1D polyclonal antibody

Alternative Name: Antigen-presenting glycoprotein CD1d; CD1.1; CD1A; CD1d; CD1D antigen; CD1D antigen d polypeptide; CD1d molecule; CD1D; Cd1d1; differentiation antigen CD1 alpha 3; HMC class I antigen like glycoprotein CD1D; Ly 38; MGC34622; R3; R3G1; T cell surface glycoprotein CD1d; Thymocyte antigen CD1D;

Immunogen: Recombinant full length Human CD1D.

Conjugate: Unconjugated

Modification: Unmodified