Product Description

CD1D Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: NCP0188P-50, NCP0188P-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Swiss-Prot: P15813

Host: Rabbit

Reactivity: Human

Applications: WB, IF

All Applications: WB: 1:2000~1:5000
IF 1:50~1:200

Background: The CD1 multigene family encodes five forms of the CD1 T cell surface glyco_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x005f_x005F_x0002_protein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 mem_x005F_x0002_brane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. CD1 anti_x0002_gens are associated with b-2-Microglobulin and expressed on cortical thymo_x005F_x0002_cytes, Langerhans cells, a B cell subset and some dendritic cells. Adaptor pro_x0002_tein complexes and CD1-associated chaperones control CD1 trafficking and the development and activation of CD1-restricted T cells. CD1D is present on human intestinal epithelial cells (IEC) and exists as a b-2-Microglobulin_x0002_independent nonglycosylated form or a b-2-Microglobulin-dependent glycosy_x0002_lated form. The human CD1D gene maps to chromosome 1q23.1 and encodes a 335 amino acid protein that influences normal T cell maturation.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CD1D polyclonal antibody detects endogenous levels of CD1D protein.

Bioworld Molecular Weight: ~ 55 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of CD1D polyclonal antibody at 1:2000 dilution
Lane 1: L02 cell membrane lysate (24ug)
Lane 2: A549 cell membrane lysate (24ug), Immunofluorescence analysis of MCF-7 cells using CD1D pAb at dilution of 1:200.

Alternative Name: Antigen-presenting glycoprotein CD1d; R3G1; CD1d; CD1D

Immunogen: Recombinant protein of human CD1D.

Conjugate: Unconjugated

Modification: Unmodified