Product Description

CD207 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA22974-50, RA22974-100

Citations, Manuals and MSDS Available upon request.

Background: CD207 molecule (CD207) Homo sapiens The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. [provided by RefSeq, Aug 2010],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: CD207; CLEC4K; C-type lectin domain family 4 member K; Langerin; CD207

Applications: WB; ELISA

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 50489

Protein MW (KDa): 38

SWISS: Q9UJ71

Source: Rabbit

Research Use Only