CD244 rabbit pAb - ES4345

CD244 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES4345-50, ES4345-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009],

Alternate Name: CD244; 2B4; Natural killer cell receptor 2B4; NK cell activation-inducing ligand; NAIL; NK cell type I receptor protein 2B4; NKR2B4; h2B4; CD244

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human CD244. AA range:101-150

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 42kD

Human Gene ID: 51744

Human SWISS Prot NO: Q9BZW8

Subcellular Location: Membrane; Single-pass type I membrane protein. Cell membrane. Receptor engagement results in a recruitment to lipid drafts essential for the subsequent tyrosine phosphorylation of the ITSMs.

Research Use Only