CD25 Monoclonal Antibody (Q22) - BT-MCA0292

CD25 Monoclonal Antibody (Q22)

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-MCA0292-20, BT-MCA0292-50, BT-MCA0292-100

Citations, Manuals and MSDS Available upon request.

Background: The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.

Research Areas: Immunology; Cancer; Neuroscience

Target Protein: IL2RA

Applications: IHC-p, IF

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Interleukin-2 receptor subunit alpha

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 30819

UniProt Accession: Human: P01589; Mouse: P01590; Rat: P26897

Synonyms: IL2RA; Interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; TAC antigen; p55; CD25

GeneID: Human: 3559; Mouse: 16184; Rat: 25704

Research Use Only